Frequently Asked Questions (FAQ) About HIV and AIDS (With Reference Citations)
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Quick Reference Index of Questions and Answers
- Do I Have HIV/AIDS? Personal Counseling and Medical Attention
- I may have been exposed to HIV. What should
I do?
- I had sex with a sex worker. What's
the risk I have contracted HIV?
I had sex with a person who's HIV positive. What's the risk I have contracted HIV?
I had sex with a person and I don't know their HIV status. What's the risk I have contracted HIV? - I have some symptoms like swollen lymph nodes, night sweats, etc. What's the risk I have HIV/AIDS?
- How soon after exposure to HIV
could I show symptoms of primary HIV infection?
- What are some hotlines I can call to get answers to my questions?
- Can AIDSvideos.org and/or Dr. Becky
Kuhn provide me personal medical advice over the Internet?
I live in a place where it's hard to get to the doctor. Can AIDSvideos.org and/or Dr. Becky Kuhn provide me personal medical advice over the Internet?
- Definition of AIDS
- What is the definition of AIDS for an adult or child 13 or older?
- What is the definition of AIDS for a child younger than 13?
- Are other definitions used elsewhere? Why?
- Origin of HIV
- When did HIV-1 originate?
- Where did HIV-1 come from?
- Where did HIV-2 come from?
- How did HIV jump from primates to humans?
- Since SIV has existed for a long time,
why did HIV-1 only jump to humans in 1931?
- HIV Transmission
- Can I contract HIV through oral sex?
Can I contract HIV through performing oral sex on a man?
Can a man contract HIV by receiving oral sex?
Can HIV be transmitted through oral sex if a condom is used? - Can I contract HIV by performing oral
sex on a woman?
Can a woman contract HIV by receiving oral sex? - Can HIV be spread through heterosexual sex?
- Can I contract HIV through vaginal sex?
- Can I contract HIV through anal sex?
- Can I contract HIV even if we use a
condom?
- Can I contract HIV through masturbation?
- Can I contract HIV through sex
with a person who tests "HIV negative" on an HIV test?
- Can I contract HIV through sex with a person who has never been exposed to HIV?
- Can I contract HIV through eating food or drinking?
- Can I contract HIV by living in the same household as an HIV+ person?
- Can I contract HIV by sharing shaving
razors or toothbrushes?
- Can I contract HIV from light / social / closed-mouthed kissing?
- Can I contract HIV from deep / "French" / open-mouthed kissing?
- Can I contract HIV from insect bites?
- Can I contract HIV from a toilet seat?
- HIV Testing
- How accurate are HIV tests?
- If I contract HIV, how soon
after exposure will I test HIV positive on an HIV test?
How long is the "window period"?
- What's the chance of a "false positive" result on an initial ELISA HIV Test?
- What's the chance of
getting a "false positive" result on both the initial ELISA and
confirmatory Western Blot Test?
- Where can I be tested for HIV?
- When I take an HIV test, how long does it take to get my result?
- To be tested for HIV, do I have to provide my real name?
- Can I take an HIV test at home?
- To be tested for HIV, do I have to give blood or be stuck with a needle?
- I tested HIV negative on my first HIV
test, but I'm stressed out waiting until I can take a follow-up test to
be SURE I'm HIV negative. What do I do?
- If You're Diagnosed with HIV/AIDS
- HIV's Connection to AIDS
- Course of the Disease in an Individual
- Does everyone who contracts HIV develop clinical AIDS?
- How long does it take for HIV to progress to clinical AIDS?
- Why don't people infected with HIV
immediately develop clinical AIDS?
- Treatment and Antiretroviral Medications (ARVs)
- How long can a person who is HIV+ on ARVs remain healthy?
- How long will a person who is HIV+ live?
- Is there a cure for HIV?
- Course of the Pandemic
Do I Have HIV/AIDS? Personal Counseling and Medical Attention
I may have been exposed to HIV. What should I do?
See a doctor. Explain your sexual history, risk factors for HIV (such as unprotected sex, needle sharing, etc.), and any symptoms. Ask to be tested for HIV, and follow any instructions the doctor gives you (such as follow-up testing at a later date).I had sex with a sex worker. What's the risk I
have contracted HIV?
I had sex with a person who's HIV positive. What's the risk I have
contracted HIV?
I had sex with a person and I don't know their HIV status. What's the
risk I have contracted HIV?
It's impossible to precisely estimate the risk that a particular person
is HIV positive. See our video "What's the Risk
That I Have Contracted HIV?" See a doctor, describe your sexual
history and risk factors for HIV, get tested for
HIV, and follow any instructions the doctor gives you (like follow-up
testing). Watch our videos Did I Just Contract HIV?
Symptoms of Primary HIV Infection and "Why EVERY Person
Should Be Tested for HIV." Go to AIDSvideos dot org and click "Risk" to learn more.(The "Risk" link takes you to the standard response we send to people who email us asking the risk that they have HIV.)
I have some symptoms like swollen lymph
nodes, night sweats, etc. What's the risk I have HIV/AIDS?
No one can diagnose anything over the Internet. Anyone with symptoms
that are persistent, severe, or possible indicators of a serious
condition should see a doctor. Describe your sexual history and risk
factors for HIV, get tested for HIV, and follow any instructions the
doctor gives you (like follow-up testing). Watch our videos "Do I Have AIDS?
Symptoms of AIDS" and "Why EVERY Person
Should Be Tested for HIV." Go to AIDSvideos dot org and click "Symptoms" to
learn more.(The "Symptoms" link takes you to the standard response we send to people who email us asking whether they are having symptoms of HIV/AIDS.)
How soon after exposure to HIV could I show symptoms of primary HIV infection?
Not everyone who contracts HIV experiences symptoms of primary HIV infection. When they do, it's "usually 2 to 6 weeks after becoming infected with HIV." ["Primary HIV Infection" article at TheBody dot com] I'm not sure what is the soonest that an individual could possibly experience symptoms of primary HIV infection; that's probably difficult to impossible to answer.What are some hotlines I can call to get answers to my questions?
United States: CDC National Prevention Information NetworkCan
AIDSvideos.org and/or Dr. Becky Kuhn provide me personal medical advice
over the Internet?
I live in a place where it's hard to
get to the doctor. Can AIDSvideos.org and/or Dr. Becky Kuhn provide me
personal medical advice over the Internet?
No. Neither AIDSvideos.org nor Dr. Kuhn provide a hotline or Internet
Q&A service. No one can diagnose conditions or provide personal
medical advice over the Internet. For personal medical advice, make an
appointment with a medical doctor and be examined. To get answers to
your questions, call the CDC
National
Prevention Information Network hotline.Definition
of AIDS
What is the definition of AIDS
for an adult or child 13 or older?
From NIAID "Evidence
that HIV Causes AIDS:" The CDC "defines AIDS in an
adult or adolescent age 13 years or older as the presence of one of 26
conditions indicative of severe immunosuppression associated with HIV
infection, such as Pneumocystis carinii pneumonia (PCP), a condition
extraordinarily rare in people without HIV infection .... A diagnosis
of AIDS also is given to HIV-infected individuals when their CD4+
T-cell count falls below 200 cells/cubic millimeter (mm3) of blood."What is the definition of AIDS for a child younger than 13?
From NIAID Evidence that HIV Causes AIDS:" "In HIV-infected children younger than 13 years, the CDC definition of AIDS is similar to that in adolescents and adults, except for the addition of certain infections commonly seen in pediatric patients with HIV."Are other definitions used
elsewhere? Why?
From NIAID:
"In many developing countries, where diagnostic facilities
may be minimal, healthcare workers use a .... [WHO] AIDS case
definition based on the presence of clinical signs associated with
immune deficiency and the exclusion of other known causes of
immunosuppression .... An expanded WHO AIDS case definition, with a
broader spectrum of clinical manifestations ... is employed in settings
where HIV antibody tests are available (WHO. Wkly Epidemiol Rec.
1994;69:273)."Origin of HIV
When did HIV-1 originate?
"[A]nalysis of the molecular divergence of SIV and HIV genes .... establishes 1931 as the date of origin of the HIV-1 M-group viruses (the principal cause of the AIDS pandemic)." [David Hillis, "AIDS: Origins of HIV," Science 9 June 2000, v288, #5472, p1757-1759. See also Korber et al, "Timing the Ancestor of the HIV-1 Pandemic Strains," Science 9 June 2000, v288, #5472, p1789-1796.](Sources: http://www.sciencemag.org/cgi/content/summary/288/5472/1757 and http://www.sciencemag.org/cgi/content/short/288/5472/1789)
Where did HIV-1 come from?
HIV-1 jumped to humans from the related SIV in chimpanzees. [Reeves JD, Doms RW. "Human immunodeficiency virus type 2." J Gen Virol. 2002 Jun;83(Pt 6):1253-65.]Where did HIV-2 come from?
HIV-2 jumped to humans from the related SIV in the sooty mangabey monkey. [Reeves JD, Doms RW. "Human immunodeficiency virus type 2." J Gen Virol. 2002 Jun;83(Pt 6):1253-65.]How did HIV jump from primates to humans?
The most likely explanation is that a hunter in the bush meat trade (in which wild animals are killed for food) probably contracted SIV from a primate he killed. For example, if the hunter had an open cut and chimpanzee blood with SIV got on the cut, that would be blood-to-blood contact enabling contagion. The SIV then evolved into HIV-1.Since SIV has existed for a long time, why did HIV-1 only jump to humans in 1931?
You could ask the same question about why H5-N1 bird flu, SARS, or Ebola infected humans recently. Viruses evolve in animals & humans all the time. It's impossible to say for sure why a virus jumps to humans at a particular moment and why it does/doesn't become permanently established within the human population. It may have mutated making it more capable of infecting humans, or humans may have had increased contact with source animals due to population growth, and travel may help it spread.HIV Transmission
Can I contract HIV through oral sex?
Can I contract HIV through performing oral sex on a man?
Can a man contract HIV by receiving oral sex?
Can HIV be transmitted through oral sex if a condom is used?
"Yes, it is possible for either
partner to become infected with HIV through performing or receiving
oral sex. There have been a few cases of HIV transmission from
performing oral sex on a person infected with HIV .... Studies have
shown that latex condoms are very effective, though not perfect, in
preventing HIV transmission when used correctly and consistently."
[CDC, "Can I get
HIV from oral sex?"] See our video "Some Ways You Can
Contract HIV and the Risk of Each One" for details. Can I contract HIV by performing oral
sex on a woman?
Can a woman contract HIV by receiving oral sex?
Yes. "The risk of HIV
transmission during cunnilingus is extremely low compared to vaginal
and anal sex. However, there have been a few cases of HIV transmission
most likely resulting from oral-vaginal sex." [CDC, Preventing
the Sexual Transmission of HIV, the Virus that Causes AIDS: What You
Should Know about Oral Sex]Can HIV be spread through heterosexual sex?
Yes. Either partner can contract HIV through heterosexual sex. This is true whether or not a condom is used. Condoms greatly reduce but do not eliminate the risk of HIV transmission. See our video "Some Ways You Can Contract HIV and the Risk of Each One" for details.Can I contract HIV through vaginal sex?
Yes. Either partner can contract HIV through vaginal sex. This is true whether or not a condom is used. Condoms greatly reduce but do not eliminate the risk of HIV transmission. See our video "Some Ways You Can Contract HIV and the Risk of Each One" for details.Can I contract HIV through anal sex?
Yes. Either partner can contract HIV through anal sex. This is true whether or not a condom is used. Condoms greatly reduce but do not eliminate the risk of HIV transmission. See our video "Some Ways You Can Contract HIV and the Risk of Each One" for details.Can I contract HIV even if we use a condom?
Yes. Condoms, if used correctly and every time, GREATLY reduce your risk of contracting HIV and significantly reduce your risk of contracting other STDs as well, but they do not GUARANTEE you won't contract HIV or other STDs. So yes, there's a risk.Can I contract HIV through masturbation?
No. HIV is a virus. You have to contract it through intimate exposure to a person who has been exposed to HIV or exposure to their bodily fluids like blood, semen, or vaginal secretions. You can't "give HIV to yourself" or "cause HIV to develop" through masturbation.Can I contract HIV through sex with a person who tests "HIV negative" on an HIV test?
Yes, if they are in the "window period" soon after contracting HIV. After a person is exposed to HIV and becomes infected, there is a "window period" during which their body has not yet developed antibodies to HIV. If a person takes a typical HIV test during this "window period," they will receive a "false negative" test result of "HIV negative," but in reality they are infected with HIV, it is present in their bodily fluids, and they can infect others.Can I contract HIV through sex with a person who hasn't been exposed to HIV?
No. HIV is a virus. You have to contract it through intimate exposure to a person who has been exposed to HIV or exposure to their bodily fluids like blood, semen, or vaginal secretions.Can I contract HIV through eating food or
drinking?
"There is no known risk of HIV
transmission to co-workers, clients, or consumers from contact in
industries such as food-service establishments" [CDC, "HIV
and Its Transmission"]
Can I contract HIV by living in the same household as an HIV+ person?
Not through ordinary social contact. "Although HIV has been transmitted between family members in a household setting, this type of transmission is very rare. These transmissions are believed to have resulted from contact between skin or mucous membranes and infected blood .... [Precautions] should be taken .... to prevent exposures to the blood of persons who are HIV infected, at risk for HIV infection, or whose infection and risk status are unknown." [CDC, "HIV and Its Transmission"]Can I contract HIV by sharing shaving razors or toothbrushes?
There is one documented case where HIV is believed to have been transmitted between brothers in the same household by sharing a shaving razor. "Practices that increase the likelihood of blood contact, such as sharing of razors and toothbrushes, should be avoided." [CDC, "HIV and Its Transmission"]Can I contract HIV from light / social / closed-mouthed kissing?
"Casual contact through closed-mouth or "social" kissing is not a risk for transmission of HIV." [CDC, "HIV and Its Transmission"]Can I contract HIV from deep / "french" / open-mouthed kissing?
"Because of the potential for contact with blood during "French" or open-mouth kissing, CDC recommends against engaging in this activity with a person known to be infected. However, the risk of acquiring HIV during open-mouth kissing is believed to be very low. CDC has investigated only one case of HIV infection that may be attributed to contact with blood during open-mouth kissing." [CDC, "HIV and Its Transmission"]Can I contract HIV from insect bites?
"[S]tudies conducted by researchers at CDC and elsewhere have shown no evidence of HIV transmission from mosquitoes or any other insects--even in areas where there are many cases of AIDS and large populations of mosquitoes .... HIV lives for only a short time inside an insect ... the insect does not become infected and cannot transmit HIV to the next human it bites ...." [CDC, "HIV Transmission"]Can I contract HIV from a toilet seat?
"Scientists and medical authorities agree that HIV does not survive well in the environment, making the possibility of environmental transmission remote .... drying of HIV-infected human blood or other body fluids reduces the theoretical risk of environmental transmission to that which has been observed--essentially zero .... no one has been identified as infected with HIV due to contact with an environmental surface." [CDC, "HIV and Its Transmission"]HIV Testing
How accurate are HIV tests?
Testing is specific & accurate. "A large study of HIV testing in 752 U.S. laboratories reported a sensitivity of 99.7% and specificity of 98.5% .... and studies in U.S. blood donors reported specificities of 99.8% and greater than 99.99% (46, 47). With confirmatory Western blot, the chance of a false-positive identification in a low-prevalence setting is about 1 in 250 000 (95% CI, 1 in 173 000 to 1 in 379 000) (48)." [Chou et al, Annals of Internal Medicine, 5 July 05, vol 143, #1, p 55-73]If I contract HIV, how soon after
exposure will I test HIV positive on an HIV test?
How long is the "window period"?
On average, it takes 25 days for a person to develop antibodies to HIV
that are detectable using the ELISA test. “Most people will develop
detectable antibodies within 2 to 8 weeks .... Ninety-seven percent of
persons will develop antibodies in the first 3 months following the
time of their infection. In very rare cases, it can take up to 6 months
to develop antibodies to HIV.” [CDC, "Deciding
If and When to Be Tested"] See our video "The Top Ten
Questions About HIV Tests" for more details.What's the chance of a "false positive" result on an initial ELISA HIV Test?
If a person gets an ELISA test result of "HIV positive," there's a 98.5% chance that their test result is correct. The chance that it was a "false positive" result is 1.5%. [Chou et al, Annals of Internal Medicine, 5 July 05, vol 143, #1, p 55-73] See our video "The Top Ten Questions About HIV Tests" for more information.What's the chance of
getting a "false positive" result on both the initial ELISA and
confirmatory Western Blot Test?
If a person gets an test result of "HIV positive" on the initial ELISA
test AND the confirmatory Western Blot Test, there's a 99.9996% chance
that their test result is correct. The chance of getting
a "false positive" result on both tests is 0.0004%, or about 1 in
250,000. [Chou et al, Annals of Internal
Medicine, 5 July 05, vol 143, #1, p
55-73] See our video "The Top Ten
Questions About HIV Tests" for more information.
Where can I be tested for HIV?
In the U.S., go to hivtest dot org and type in your ZIP code to find a testing location. Elsewhere, visit your doctor, public health clinic, or STD testing center.When I take an HIV test, how long does it take to get my result?
Oral tests for HIV can give you a result within as little as 20 minutes. See our video "The Top Ten Questions About HIV Tests" for more information.To be tested for HIV, do I have to provide my real name?
No. In the U.S., some states allow "Anonymous Testing," which means you don't have to give any name. Other U.S. states require “Confidential, Name-Based Testing," which means that you have provide a name, but you don't have to give your real name. See our video "The Top Ten Questions About HIV Tests" for more information.Can I take an HIV test at home?
Yes. You can buy a home-based test kit for HIV-1 (the most common strain of HIV outside of Africa) at any pharmacy in the U.S. and in many other countries as well. See our video "The Top Ten Questions About HIV Tests" for more information.To be tested for HIV, do I have to give blood or be stuck with a needle?
Not for the first test. The first test is usually done today with a simple oral swab or a finger stick. If you test positive on the first test, you will need to give blood for the second test, which is a Western Blot. But you only have to give a little bit of blood. See our video "The Top Ten Questions About HIV Tests" for more information.I tested HIV negative on my first HIV
test, but I'm stressed out waiting until I can take a follow-up test to
be SURE I'm HIV negative. What do I do?
It's understandable that you would feel stress while you wait for final
confirmation of your HIV test status. If stress is causing you problems
like difficulty concentrating on work or studies, difficulty sleeping,
or depression, consider seeing a licensed mental health professional
for counseling to help you manage the stress during this period. If you
can't sleep, ask a doctor whether a prescription sleeping aid would be
right to help you through this period. Regular exercise may also help.If You're Diagnosed with HIV/AIDS
"If I'm diagnosed with HIV/AIDS, I'm going to kill myself!"
Don't kill yourself if you're diagnosed with HIV/AIDS! See our videos "Is HIV a Death Sentence?" and "'If I'm HIV Positive, I'm Going to Commit Suicide!' (Don't)" and "Personal Testimonial of Cory Norlund" for details. If people with HIV follow their doctor's instructions and take care of their general health, with a little luck they can live a normal lifespan and have good quality of life.Rather than killing yourself if you test HIV+, how about you (1) discuss your concerns with your doctor, (2) follow their instructions, (3) get counseling from a licensed mental health provider to help you deal with the understandable stress of an HIV+ diagnosis, and (4) see how things go for a while, talk with trusted friends and family, and not make any drastic and irreversible decisions? Just take life one day at a time. If you feel suicidal now, go to the nearest emergency room right away.
HIV's Connection to AIDS
How do we know that HIV is the cause of AIDS?
Because HIV infection is a serious condition that is incurable and usually develops into clinical AIDS which is frequently fatal, it would not be ethical to perform an experiment where a person was deliberately, knowingly infected with HIV to demonstrate the progression to clinical AIDS. However, there are multiple independent lines of evidence proving that HIV is the cause of AIDS by other means. For full details with references, see "The Evidence That HIV Causes AIDS" and "The Relationship Between Human Immunodeficiency Virus and Acquired Immunodeficiency Syndrome" among many other sources. Here are a few quick summaries:- NIAID:
By 12/31/94, "CDC had
received reports of 42 health care workers in the United States with
documented, occupationally acquired HIV infection, of whom 17 have
developed AIDS in the absence of other risk factors .... These
individuals all had evidence of HIV seroconversion following a discrete
percutaneous or mucocutaneous exposure to blood, body fluids or other
clinical laboratory specimens containing HIV." [CDC, "HIV/AIDS
surveillance report, 1994 year-end edition," 1995a;6(no.2).]
- NIAID "Evidence That HIV Causes AIDS:" "through December 1999, the CDC had received reports of 56 health care workers in the United States with documented, occupationally acquired HIV infection, of whom 25 have developed AIDS in the absence of other risk factors."
- NIAID "Relationship Between HIV and AIDS": Known HIV seroconversion followed by development of AIDS "has been repeatedly observed in pediatric and adult blood transfusion," in mother-to-child transmission, "and in studies of hemophilia, injection drug use, and sexual transmission in which the time of seroconversion can be documented using serial blood samples." [Ward 89, Ashton 94, ECS 91&92, Turner 93, Blanche 94,Goedert 89, Rezza 89, Biggar 90, Alcabes 93, Gisecke 90, Buchbinder 94, Sabin 93]
- NIAID "Evidence That HIV Causes AIDS:" "in a 10-year study in the Netherlands, researchers followed 11 children who had become infected with HIV as neonates by small aliquots of plasma from a single HIV-infected donor. During the 10-year period, eight of the children died of AIDS. Of the remaining three children, all showed a progressive decline in cellular immunity, and two of the three had symptoms probably related to HIV infection (van den Berg et al. Acta Paediatr 1994;83:17)"
- NIAID "Evidence:" "transmission of HIV from a Florida dentist to six patients has been documented by genetic analyses of virus isolated from both .... The dentist and three of the patients developed AIDS and died, and at least one of the other patients has developed AIDS. Five of the patients had no HIV risk factors other than multiple visits to the dentist for invasive procedures (O'Brien, Goedert. Curr Opin Immunol 1996;8:613; O'Brien, 1997; Ciesielski et al. Ann Intern Med 1994;121:886)."
- NIAID: "Among HIV-infected patients who receive anti-HIV therapy, those whose viral loads are driven to low levels are much less likely to develop AIDS or die than patients who do not respond to therapy. Such an effect would not be seen if HIV did not have a central role in causing AIDS." [Montaner AIDS 1998;12:F23; Palumbo JAMA 1998;279:756; O'Brien NEJM 1996;334:426; Katzenstein NEJM 1996;335:1091; Marschner J Infect Dis 1998;177:40; Hammer NEJM 1997;337:725; Cameron Lancet 1998;351:543]
- NIAID: Cases have been documented where HIV+ mothers gave birth to twins where one was HIV-infected and the other wasn't. "The HIV-infected children developed AIDS, while the other children remained clinically and immunologically normal." [Park. J Clin Microbiol 1987;25:1119; Menez-Bautista. Am J Dis Child 1986;140:678; Thomas. Pediatrics 1990;86:774; Young. Pediatr Infect Dis J 1990;9:454; Barlow and Mok. Arch Dis Child 1993;68:507; Guerrero Vazquez. An Esp Pediatr 1993;39:445]
- NIAID: Animal models also show that HIV causes AIDS. "Chimpanzees experimentally infected with HIV have developed severe immunosuppression and AIDS. In severe combined immunodeficiency (SCID) mice given a human immune system, HIV produces similar patterns of cell killing and pathogenesis as seen in people. HIV-2 .... also causes an AIDS-like syndrome in baboons." [O'Neil et al. J Infect Dis 2000;182:1051; Aldrovandi et al. Nature 1993;363:732; Locher et al. Arch Pathol Lab Med 1998;22:523]
Course of the Disease in an Individual
Does everyone who contracts HIV develop clinical AIDS?
No. Some will die of other unrelated causes (e.g. a car accident) or natural causes before HIV progresses to clinical AIDS. Some have natural resistance to HIV that may greatly slow or totally prevent the progression from HIV to clinical AIDS. Some go on antiretroviral medication before their HIV disease meets the criteria for clinical AIDS and as a result never get the opportunistic infection or CD4 cell count that would lead to a diagnosis of clinical AIDS. However, all but a few HIV positive individuals progress to AIDS within 20 years. ["Course of HIV Infection", NIH, 1995]How long does it take for HIV to progress to clinical AIDS?
From NIAID "Evidence:" "The median period of time between infection with HIV and the onset of clinically apparent disease is approximately 10 years in industrialized countries, according to prospective studies of homosexual men .... Similar estimates ... have been made for HIV-infected blood-transfusion recipients, injection-drug users and adult hemophiliacs." [Alcabes et al. Epidemiol Rev 1993;15:303] All but a few progress to AIDS within 20 years. ["Course of HIV Infection", NIH, 1995]Why don't people infected with HIV immediately develop clinical AIDS?
HIV is only one of many viruses that produce an acute symptomatic infection, then may have a long period where the infected person experiences few no symptoms, then later in life develops symptoms again. Examples include: chicken pox, which causes an acute infection and then after decades without symptoms leads to shingles in about 1/7 of infected people; recurring oral herpex simplex ("cold sores') which may go a long time with no symptoms and then recur; etc.The reasons for these asymptomatic periods can be completely different. The chicken pox virus (varicella-zoster virus) and herpes simplex virus type 1 remain dormant in the nerves and can reactivate causing localized shingles or cold sores respectively. HIV usually appears asymptomatic because the body's immune system is holding it at bay, generating new CD4 cells as fast as HIV kills them. When the body falls behind in this running battle, HIV can progress to clinical AIDS.
Treatment and Antiretroviral Medications (ARVs)
How long can a person who is HIV+ on ARVs remain healthy?
If a person who is on ARVs takes them exactly as prescribed, it appears that they may be able to prevent the progression from HIV+ to clinical AIDS indefinitely. (We don't know how long for sure since ARVs have only been in use since the 90s.) However, if they miss doses, it's likely that HIV will develop resistance to their ARVs and they'll need to change medications. So rigorous compliance is critical.How long will a person who is HIV+ live?
It's impossible to accurately predict how long a particular HIV+ individual will live. It depends on their HIV strain(s), genetic makeup, treatment compliance, and general health. If an HIV+ person follows their doctor's instructions, takes any prescribed medications as directed, and takes care of their general nutrition, health, and sleep, they may be able to live a normal quality & quantity of life and die of natural causes.Is there a cure for HIV?
There is no cure for HIV. Recently, a single HIV+ person who needed a bone marrow transplant for leukemia had his HIV put into "functional remission" by receiving a bone marrow transplant from a person who had a natural genetic resistance to HIV. However, this option is not appropriate as general therapy for HIV alone because of the risk of dying from a bone marrow transplant is generally higher than the risk of dying from HIV that's being managed correctly.Course of the Pandemic
Why didn't an epidemic occur immediately after the first known HIV infections?
"HIV did not become epidemic until 20 to 30 years later [after known infection in 1959], perhaps because of the migration of poor and young sexually active individuals from rural areas to urban centers in developing countries, with subsequent return migration and, internationally, due to civil wars, tourism, business travel and the drug trade" (NIAID citing Quinn, "Population migration and the spread of types 1 and 2 human immunodeficiency viruses," Proc Natl Acad Sci USA 1994;91(7):2407-14.)Reuse Permissions
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Additional Resources
- http://www.aidsmap.com/
Patient Information
- http://aidstruth.org/hiv-aids-science.php
- http://aidstruth.org/debunking-denialist-myths.php
- http://www.avert.org/evidence.htm
- http://www.aegis.com/topics/mdelaney.html
- National Institute of Allergy and Infectious Disease, "The
Relationship Between Human Immunodeficiency Virus and Acquired
Immunodeficiency Syndrome" at http://www.niaid.nih.gov/topics/HIVAIDS/Understanding/howHIVCausesAIDS/Pages/relationshipHIVAIDS.aspx
- National Institute of Allergy and Infectious Disease, "The Evidence That HIV Causes AIDS" at http://www.niaid.nih.gov/topics/hivaids/understanding/howhivcausesaids/pages/hivcausesaids.aspx